Biotech catalysts, October 2027

27 tracked events across 23 companies

Clinical trial milestones, FDA decision dates, SEC filings and earnings scheduled for October 2027, compiled from ClinicalTrials.gov and SEC EDGAR.

DateTickerEventTypePhase
October 1, 2027 NVS A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas Trial Milestone Phase 1/Phase 2
October 2, 2027 AMGN A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes Mellitus Trial Milestone Phase 1
October 4, 2027 NVO A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes Trial Milestone Phase 2
October 7, 2027 ARGX A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP Trial Milestone Phase 3
October 11, 2027 REGN Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of Cytokine Release Syndrome (CRS) Trial Milestone Phase 4
October 12, 2027 MRK A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004) Trial Milestone Phase 2
October 13, 2027 SNY A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Trial Milestone Phase 1/Phase 2
October 15, 2027 ARGX ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis Trial Milestone Phase 2
October 15, 2027 ONC A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy Trial Milestone Phase 2/Phase 3
October 15, 2027 NBIX NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia Trial Milestone Phase 3
October 15, 2027 IBRX Study for Participants With Relapsed/Refractory Non-Hodgkin Lymphoma Trial Milestone Phase 1
October 15, 2027 MIRM Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM) Trial Milestone Phase 2
October 15, 2027 EYPT CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME Trial Milestone Phase 3
October 15, 2027 EYPT COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME Trial Milestone Phase 3
October 15, 2027 PHAR Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease Trial Milestone Phase 2
October 15, 2027 ORKA Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis Trial Milestone Phase 2
October 15, 2027 CLYM A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy Trial Milestone Phase 2
October 15, 2027 SYRE A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial) Trial Milestone Phase 2
October 16, 2027 IMCR IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301) Trial Milestone Phase 3
October 20, 2027 PHAT A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease Through 24 Weeks Trial Milestone Phase 3
October 24, 2027 GSK A Study of Dostarlimab in Participants With Untreated Locally Advanced Rectal Cancer in China Trial Milestone Phase 2
October 25, 2027 PFE A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer Trial Milestone Phase 1/Phase 2
October 29, 2027 GSK Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial Trial Milestone Phase 3
October 30, 2027 ONC A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Trial Milestone Phase 3
October 30, 2027 PBYI A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer Trial Milestone Phase 2
October 31, 2027 BCAX Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors Trial Milestone Phase 1
October 31, 2027 APLM A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis Trial Milestone Phase 2

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NVS · AMGN · NVO · ARGX · REGN · MRK · SNY · ONC · NBIX · IBRX · MIRM · EYPT · PHAR · ORKA · CLYM · SYRE · IMCR · PHAT · GSK · PFE · PBYI · BCAX · APLM