SYRE catalyst calendar

Spyre Therapeutics, Inc.

Upcoming catalysts
5
Cash runway
8.5 months
Cash & investments
$162M

Spyre Therapeutics, Inc. is tracked here for clinical trial milestones, SEC filings and earnings dates. Focus area: Pharmaceutical Preparations.

The next scheduled catalyst is A Study of SPY072 in Rheumatic Disease on October 31, 2026. There are 5 upcoming events on record.

Cash runway is approximately 8.5 months based on the most recent reported cash position and quarterly operating burn as of 2026-06-30.

Upcoming catalysts

DateEventTypePhase
October 31, 2026 A Study of SPY072 in Rheumatic Disease Trial Milestone Phase 2
November 18, 2026 A Study of SPY003-207 in Healthy Volunteers Trial Milestone Phase 1
June 15, 2027 A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis Trial Milestone Phase 2
October 15, 2027 A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial) Trial Milestone Phase 2
March 2, 2029 Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD Trial Milestone Phase 2

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Recent history

DateEventTypePhase
October 7, 2026 8-K filed: Material agreement Corporate —
September 8, 2026 8-K filed: Reg FD disclosure, Other event Filing —
August 25, 2026 8-K filed: Reg FD disclosure, Other event Filing —
August 19, 2026 A Study of SPY002-091 in Healthy Volunteers Trial Milestone Phase 1
August 4, 2026 Quarterly results filed (8-K) Earnings —
July 28, 2026 A Study of SPY002-072 in Healthy Volunteers Trial Milestone Phase 1
June 15, 2026 8-K filed: Reg FD disclosure, Other event Filing —
June 1, 2026 8-K filed: Other event Filing —
May 29, 2026 8-K filed: Leadership change Corporate —
May 5, 2026 Quarterly results filed (8-K) Earnings —
April 16, 2026 8-K filed: Material agreement Corporate —
April 13, 2026 8-K filed: Reg FD disclosure, Other event Filing —
April 13, 2026 Quarterly results filed (8-K) Earnings —
March 10, 2026 A Study of SPY001-001 in Healthy Volunteers Trial Milestone Phase 1
February 19, 2026 Quarterly results filed (8-K) Earnings —
January 12, 2026 8-K filed: Reg FD disclosure Filing —
November 4, 2025 Quarterly results filed (8-K) Earnings —
October 15, 2025 8-K filed: Material agreement Corporate —
October 14, 2025 Quarterly results filed (8-K) Earnings —
August 5, 2025 Quarterly results filed (8-K) Earnings —
June 17, 2025 8-K filed: Reg FD disclosure, Other event Filing —
May 8, 2025 Quarterly results filed (8-K) Earnings —

About this data

Trial milestones come from the ClinicalTrials.gov v2 API, filings from SEC EDGAR, and financial figures from SEC XBRL company facts. Dates marked est. are projected rather than company-confirmed. This is an information tool, not investment advice — verify anything you act on against the linked primary source.

Last updated 2026-10-14.