Biotech catalysts, December 2026

149 tracked events across 105 companies

Clinical trial milestones, FDA decision dates, SEC filings and earnings scheduled for December 2026, compiled from ClinicalTrials.gov and SEC EDGAR.

DateTickerEventTypePhase
December 1, 2026 BIIB A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) Trial Milestone Phase 3
December 1, 2026 VNDA A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use Trial Milestone Phase 3
December 1, 2026 TGTX A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders Trial Milestone Phase 1
December 1, 2026 RNAC Descartes-08 for Patients With Systemic Lupus Erythematosus Trial Milestone Phase 2
December 3, 2026 GSK A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults Trial Milestone Phase 1
December 3, 2026 REGN A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body Trial Milestone Phase 2
December 3, 2026 est. WVE Next quarterly earnings (projected) Earnings —
December 4, 2026 JNJ A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms Trial Milestone Phase 1
December 4, 2026 REGN A First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy Adults Trial Milestone Phase 1
December 6, 2026 est. BMRN Next quarterly earnings (projected) Earnings —
December 6, 2026 est. OCGN Next quarterly earnings (projected) Earnings —
December 8, 2026 NVS A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction Trial Milestone Phase 1
December 8, 2026 JNJ A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer Trial Milestone Phase 1
December 8, 2026 est. PCRX Next quarterly earnings (projected) Earnings —
December 9, 2026 INCY Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa Trial Milestone Phase 1
December 9, 2026 est. EYPT Next quarterly earnings (projected) Earnings —
December 10, 2026 est. MRNA Propionic Acidemia (mRNA-3927) — Registrational Data Trial Readout Registrational
December 10, 2026 est. SMMT Next quarterly earnings (projected) Earnings —
December 10, 2026 est. CGEM Next quarterly earnings (projected) Earnings —
December 11, 2026 est. IRON Next quarterly earnings (projected) Earnings —
December 11, 2026 est. CERS Next quarterly earnings (projected) Earnings —
December 11, 2026 est. XNCR Next quarterly earnings (projected) Earnings —
December 12, 2026 est. ANRO Next quarterly earnings (projected) Earnings —
December 12, 2026 est. OTLK Next quarterly earnings (projected) Earnings —
December 13, 2026 est. REGN Next quarterly earnings (projected) Earnings —
December 13, 2026 NVO Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected) Trial Milestone Phase 1
December 13, 2026 est. ALKS Next quarterly earnings (projected) Earnings —
December 14, 2026 GSK A Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Months After a First Dose at 12 to 15 Months of Age Trial Milestone Phase 3
December 14, 2026 AMGN Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab) Trial Milestone Phase 3
December 14, 2026 est. OLMA Next quarterly earnings (projected) Earnings —
December 14, 2026 est. ATXI Next quarterly earnings (projected) Earnings —
December 15, 2026 JNJ A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors Trial Milestone Phase 1
December 15, 2026 ABBV A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants Trial Milestone Phase 1
December 15, 2026 ABBV Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab Trial Milestone Phase 2
December 15, 2026 ABBV A Study to Evaluate the Safety and Pharmacokinetics of Multiple Doses Upadacitinib, Tofacitinib, and Baricitinib in Healthy Adult Volunteers Trial Milestone Phase 1
December 15, 2026 ABBV A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Trial Milestone Phase 3
December 15, 2026 ARGX A Study to Assess the Absolute Bioavailability and How Adimanebart SC Moves Through the Body in Healthy Adult Participants Trial Milestone Phase 1
December 15, 2026 IONS A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE) Trial Milestone Phase 3
December 15, 2026 VNDA Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder Trial Milestone Phase 3
December 15, 2026 EXEL Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma Trial Milestone Phase 3
December 15, 2026 AAPG Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLL Trial Milestone Phase 2
December 15, 2026 AXSM Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN) Trial Milestone Phase 3
December 15, 2026 AXSM Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol Trial Milestone Phase 3
December 15, 2026 ARWR Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2 Trial Milestone Phase 1
December 15, 2026 PRAX A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety Trial Milestone Phase 3
December 15, 2026 PRAX A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine Trial Milestone Phase 3
December 15, 2026 KPTI A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma Trial Milestone Phase 2/Phase 3
December 15, 2026 KPTI Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) Trial Milestone Phase 2
December 15, 2026 MDGL A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) Trial Milestone Phase 3
December 15, 2026 MANE Safety and Efficacy of VDPHL01 in Males With AGA Trial Milestone Phase 3
December 15, 2026 EIKN A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC Trial Milestone Phase 2
December 15, 2026 KARD Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension Trial Milestone Phase 2
December 15, 2026 VIR A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide Trial Milestone Phase 3
December 15, 2026 CORT Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome Trial Milestone Phase 2
December 15, 2026 DNTH A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy Trial Milestone Phase 2
December 15, 2026 RCUS A Study to Investigate the Safety, Tolerability, and PK of AB102 in Healthy Participants Trial Milestone Phase 1
December 15, 2026 TARA Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age Trial Milestone Phase 2
December 15, 2026 DNLI A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN) Trial Milestone Phase 1/Phase 2
December 15, 2026 KRYS A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa Trial Milestone Phase 3
December 15, 2026 KRYS A Study Assessing KB407 for the Treatment of Cystic Fibrosis Trial Milestone Phase 1
December 15, 2026 KRYS A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis Trial Milestone Phase 1/Phase 2
December 15, 2026 MDWD A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE) Trial Milestone Phase 3
December 15, 2026 OCS A Clinical Study Evaluating Licaminlimab for Dry Eye Disease Trial Milestone Phase 2/Phase 3
December 15, 2026 AVIR Study of AT-587 in Healthy Subjects Trial Milestone Phase 1
December 15, 2026 AVIR C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV Trial Milestone Phase 3
December 15, 2026 DCTH Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease Trial Milestone Phase 2
December 15, 2026 UTHR A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension Trial Milestone Phase 3
December 15, 2026 ABVX Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease Trial Milestone Phase 2
December 15, 2026 est. PHAT Next quarterly earnings (projected) Earnings —
December 15, 2026 BEAM A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL) Trial Milestone Phase 1/Phase 2
December 15, 2026 ORIC ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC Trial Milestone Phase 1
December 15, 2026 KURA Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia Trial Milestone Phase 1
December 15, 2026 PCRX ZILRETTA in Subjects With Shoulder Osteoarthritis Trial Milestone Phase 3
December 15, 2026 ANRO Study of ALTO-300 in MDD Trial Milestone Phase 2
December 15, 2026 GNLX Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076) Trial Milestone Phase 3
December 15, 2026 LXEO Gene Therapy for ACM Due to a PKP2 Pathogenic Variant Trial Milestone Phase 1/Phase 2
December 15, 2026 TRAW This is an Early-stage Clinical Trial to Determine a Safe and Effective Dose for Tivoxavir Marboxil in Patients With Mild to Moderate Influenza Trial Milestone Phase 2
December 15, 2026 AVLN AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02 (Nintedanib Solution) in IPF Trial Milestone Phase 2
December 15, 2026 OMER Long-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria Trial Milestone Phase 2
December 15, 2026 PVCT Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency in Pediatric Patients Trial Milestone Phase 3
December 15, 2026 DMAC Treatment of Acute Ischemic Stroke (ReMEDy2 Trial) Trial Milestone Phase 2/Phase 3
December 15, 2026 KYMR First-in-human Study of Orally Administered KT-579 in Healthy Adult Participants Trial Milestone Phase 1
December 15, 2026 ALDX A Clinical Trial Evaluating Patients With Primary Vitreoretinal Lymphoma Trial Milestone Phase 3
December 15, 2026 GOSS Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT) Trial Milestone Phase 3
December 15, 2026 ACIU A Study Investigating the Safety, Absorption, Elimination, and the Effect on the Immune System of ACI-19764 in Healthy Participants and in Participants With Cardiovascular Risk Factors Trial Milestone Phase 1
December 15, 2026 AKBA SAD and MAD Study of AKB-9090 in Healthy Adult Participants Trial Milestone Phase 1
December 15, 2026 CERS A Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1 Trial Milestone Phase 2
December 15, 2026 LTRN A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma Trial Milestone Phase 2
December 15, 2026 ALZN A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder Trial Milestone Phase 1/Phase 2
December 15, 2026 CGEM A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus Trial Milestone Phase 1
December 16, 2026 MRNA A Study to Investigate Safety and Tolerability of mRNA-0184 Administered Subcutaneously in Healthy Participants Trial Milestone Phase 1
December 16, 2026 est. DYN Next quarterly earnings (projected) Earnings —
December 17, 2026 BMY A Study to Assess the Relative Bioavailability of BMS-986435 and Food Effect on the BMS-986435 in Healthy Adult Participants Trial Milestone Phase 1
December 17, 2026 est. VCEL Next quarterly earnings (projected) Earnings —
December 17, 2026 SRRK A Single- and Multiple-Ascending Dose Study of SRK-439 in Healthy Adults Trial Milestone Phase 1
December 18, 2026 est. DFTX Next quarterly earnings (projected) Earnings —
December 18, 2026 est. RYTM Next quarterly earnings (projected) Earnings —
December 18, 2026 est. NVCR Next quarterly earnings (projected) Earnings —
December 18, 2026 est. MBX Next quarterly earnings (projected) Earnings —
December 18, 2026 est. LRMR Next quarterly earnings (projected) Earnings —
December 20, 2026 est. RIGL Next quarterly earnings (projected) Earnings —
December 21, 2026 est. JAZZ Next quarterly earnings (projected) Earnings —
December 21, 2026 est. BCRX Next quarterly earnings (projected) Earnings —
December 22, 2026 est. ACAD Next quarterly earnings (projected) Earnings —
December 22, 2026 est. SNDX Next quarterly earnings (projected) Earnings —
December 22, 2026 est. DCTH Next quarterly earnings (projected) Earnings —
December 22, 2026 ENSC Single Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102) Trial Milestone Phase 1
December 23, 2026 est. MIRM Next quarterly earnings (projected) Earnings —
December 23, 2026 est. SRPT Next quarterly earnings (projected) Earnings —
December 23, 2026 est. KYMR Next quarterly earnings (projected) Earnings —
December 23, 2026 est. TRDA Next quarterly earnings (projected) Earnings —
December 23, 2026 est. AKBA Next quarterly earnings (projected) Earnings —
December 26, 2026 INCY A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa Trial Milestone Phase 3
December 26, 2026 est. IONS Next quarterly earnings (projected) Earnings —
December 27, 2026 est. KNSA Next quarterly earnings (projected) Earnings —
December 28, 2026 GSK A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study Trial Milestone Phase 2
December 28, 2026 est. GKOS Next quarterly earnings (projected) Earnings —
December 29, 2026 REGN A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia Trial Milestone Phase 2
December 29, 2026 ALNY A Study to Evaluate ALN-4285 in Adult Healthy Volunteers Trial Milestone Phase 1
December 30, 2026 NVS Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment Trial Milestone Phase 3
December 30, 2026 JNJ Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms Trial Milestone Phase 3
December 30, 2026 SVA Immunogenicity and Safety of Rabies Vaccine (Serum-free Vero Cell) in a Pre-exposure Prophylaxis Regimen Trial Milestone Phase 3
December 30, 2026 QNRX Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome Trial Milestone Phase 2/Phase 3
December 30, 2026 QNRX Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome Trial Milestone Phase 2/Phase 3
December 30, 2026 SUPN BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures Trial Milestone Phase 1/Phase 2
December 30, 2026 RNAC Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis Trial Milestone Phase 3
December 30, 2026 SLS Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML Trial Milestone Phase 1/Phase 2
December 30, 2026 NTHI NEO100 and High-Grade Meningioma Trial Milestone Phase 2
December 30, 2026 TCRX A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors Trial Milestone Phase 1
December 31, 2026 GSK Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors Trial Milestone Phase 1
December 31, 2026 JNJ A Long-term Extension Study of PCI-32765 (Ibrutinib) Trial Milestone Phase 3
December 31, 2026 JNJ ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer Trial Milestone Phase 1
December 31, 2026 AMGN Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC) Trial Milestone Phase 1
December 31, 2026 NVO A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants Trial Milestone Phase 1
December 31, 2026 ARGX A Study to Assess the Safety of ARGX-124 in Healthy Volunteers Trial Milestone Phase 1
December 31, 2026 ONC A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors Trial Milestone Phase 1
December 31, 2026 ONC A Study to Evaluate Long-term Safety of Zanubrutinib Regimens in Participants With B-Cell Malignancies Who Participated in BeiGene Parent Studies of Zanubrutinib Trial Milestone Phase 3
December 31, 2026 AAPG Global Trial in APG2575 for Patients With CLL/SLL Trial Milestone Phase 3
December 31, 2026 JAZZ A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors Trial Milestone Phase 2
December 31, 2026 RVMD Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors Trial Milestone Phase 1
December 31, 2026 INBS Evaluate the Safety, Tolerability of BAT6026 Trial Milestone Phase 1/Phase 2
December 31, 2026 MRNA A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations Trial Milestone Phase 4
December 31, 2026 INSM An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH) Trial Milestone Phase 2/Phase 3
December 31, 2026 VIR A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV Infection Trial Milestone Phase 3
December 31, 2026 SRPT Study of SRP-1003 in Participants With Type 1 Myotonic Dystrophy Trial Milestone Phase 1/Phase 2
December 31, 2026 VTRS A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus Trial Milestone Phase 3
December 31, 2026 ANNX An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study) Trial Milestone Phase 3
December 31, 2026 SUPN Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder Trial Milestone Phase 2
December 31, 2026 MNOV MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia Trial Milestone Phase 2

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BIIB · VNDA · TGTX · RNAC · GSK · REGN · WVE · JNJ · BMRN · OCGN · NVS · PCRX · INCY · EYPT · MRNA · SMMT · CGEM · IRON · CERS · XNCR · ANRO · OTLK · NVO · ALKS · AMGN · OLMA · ATXI · ABBV · ARGX · IONS · EXEL · AAPG · AXSM · ARWR · PRAX · KPTI · MDGL · MANE · EIKN · KARD · VIR · CORT · DNTH · RCUS · TARA · DNLI · KRYS · MDWD · OCS · AVIR · DCTH · UTHR · ABVX · PHAT · BEAM · ORIC · KURA · GNLX · LXEO · TRAW · AVLN · OMER · PVCT · DMAC · KYMR · ALDX · GOSS · ACIU · AKBA · LTRN · ALZN · DYN · BMY · VCEL · SRRK · DFTX · RYTM · NVCR · MBX · LRMR · RIGL · JAZZ · BCRX · ACAD · SNDX · ENSC · MIRM · SRPT · TRDA · KNSA · GKOS · ALNY · SVA · QNRX · SUPN · SLS · NTHI · TCRX · ONC · RVMD · INBS · INSM · VTRS · ANNX · MNOV