KPTI catalyst calendar

Karyopharm Therapeutics Inc.

Upcoming catalysts
6
Cash runway
7.3 months
Cash & investments
$55M
Phase 3 programs
6

Karyopharm Therapeutics Inc. is tracked here for clinical trial milestones, SEC filings and earnings dates. Focus area: Pharmaceutical Preparations.

The next scheduled catalyst is Next quarterly earnings (projected) on October 22, 2026, a projected date rather than a confirmed one. There are 6 upcoming events on record.

Cash runway is approximately 7.3 months based on the most recent reported cash position and quarterly operating burn as of 2026-06-30.

Across 28 concluded trials, 43% reached completion rather than being terminated or withdrawn.

Upcoming catalysts

DateEventTypePhase
October 22, 2026 est. Next quarterly earnings (projected) Earnings —
December 15, 2026 A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma Trial Milestone Phase 2/Phase 3
December 15, 2026 Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) Trial Milestone Phase 2
April 15, 2027 Selinexor and Backbone Treatments of Multiple Myeloma Patients Trial Milestone Phase 1/Phase 2
June 15, 2027 A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia Trial Milestone Phase 2
January 15, 2028 A Study of Selinexor (Seli) + Low-dose Dexamethasone (LDD) in Penta-refractory Multiple Myeloma (MM), Seli and Bortezomib + LDD in Triple-class Refractory MM. Trial Milestone Phase 2

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Recent history

DateEventTypePhase
October 14, 2026 8-K filed: Other event Filing —
September 15, 2026 A Study to Evaluate Single Agent Selinexor Versus Physician's Choice in Participants With Previously Treated Myelofibrosis Trial Milestone Phase 2
September 11, 2026 8-K filed: Material agreement, Other event Corporate —
August 31, 2026 8-K filed: Other event Filing —
August 13, 2026 Quarterly results filed (8-K) Earnings —
July 31, 2026 8-K filed: Other event Filing —
July 17, 2026 8-K filed: Leadership change Corporate —
May 28, 2026 8-K filed: Leadership change Corporate —
May 22, 2026 Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma Trial Milestone Phase 3
May 14, 2026 Quarterly results filed (8-K) Earnings —
March 27, 2026 8-K filed: Other event Filing —
March 24, 2026 8-K filed: Material agreement, Reg FD disclosure, Other event Corporate —
March 3, 2026 8-K filed: Material agreement, Other event Corporate —
February 20, 2026 Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis Trial Milestone Phase 3
February 12, 2026 Quarterly results filed (8-K) Earnings —
January 12, 2026 Quarterly results filed (8-K) Earnings —
November 3, 2025 Quarterly results filed (8-K) Earnings —
October 14, 2025 8-K filed: Material agreement, Other event Corporate —
October 8, 2025 Quarterly results filed (8-K) Earnings —
September 11, 2025 8-K filed: Leadership change Corporate —
August 11, 2025 Quarterly results filed (8-K) Earnings —
July 11, 2025 8-K filed: Reg FD disclosure Filing —
May 29, 2025 8-K filed: Leadership change Corporate —
May 12, 2025 Quarterly results filed (8-K) Earnings —
August 31, 2024 Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications Trial Milestone Phase 1/Phase 2
July 31, 2024 Relative Bioavailability/Bioequivalence of Different Formulations of Selinexor, the Impact of Hepatic Impairment on Selinexor Pharmacokinetics, Tolerability and Antitumor Activity of Selinexor Combination Treatment Trial Milestone Phase 1/Phase 2
September 22, 2023 Safety and Efficacy of Selinexor in Combination With Pembrolizumab in Recurrent Advanced Melanoma Trial Milestone Phase 2
July 3, 2023 A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma Trial Milestone Phase 1/Phase 2
June 24, 2022 A Study to Evaluate the Safety and Efficacy of Selinexor With or Without Pembrolizumab Versus Standard of Care in Previously Treated Metastatic Colorectal Cancer With RAS Mutations Trial Milestone Phase 2
January 22, 2022 Maintenance With Selinexor/Placebo After Combination Chemotherapy in Participants With Endometrial Cancer [SIENDO] Trial Milestone Phase 3

About this data

Trial milestones come from the ClinicalTrials.gov v2 API, filings from SEC EDGAR, and financial figures from SEC XBRL company facts. Dates marked est. are projected rather than company-confirmed. This is an information tool, not investment advice — verify anything you act on against the linked primary source.

Last updated 2026-10-14.