| November 1, 2027 |
ONC |
A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors |
Trial Milestone |
Phase 1 |
| November 12, 2027 |
AZN |
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
ABBV |
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab |
Trial Milestone |
Phase 1 |
| November 15, 2027 |
ARGX |
A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by Prefilled Syringe in Kidney Transplant Recipients With Antibody-Mediated Rejection (AMR) |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
BNTX |
A First-in-human, Dose Escalation and Indication Expansion Study of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors |
Trial Milestone |
Phase 1/Phase 2 |
| November 15, 2027 |
NBIX |
NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia |
Trial Milestone |
Phase 3 |
| November 15, 2027 |
VNDA |
Randomized Withdrawal Study in Patients With Schizophrenia |
Trial Milestone |
Phase 3 |
| November 15, 2027 |
VNDA |
Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia |
Trial Milestone |
Phase 3 |
| November 15, 2027 |
EXEL |
A Study of XB371 Administered in Participants With Locally Advanced or Metastatic Solid Tumors |
Trial Milestone |
Phase 1 |
| November 15, 2027 |
MDGL |
Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 Fibrosis |
Trial Milestone |
Phase 4 |
| November 15, 2027 |
MDGL |
Resmetirom in Patients With MASH and HFpEF |
Trial Milestone |
Phase 1 |
| November 15, 2027 |
RNAC |
Descartes-08 in Autoantibody Myositis |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
UTHR |
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF) |
Trial Milestone |
Phase 3 |
| November 15, 2027 |
VERA |
Atacicept in Multiple Glomerular Diseases |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
RLMD |
A Study to Evaluate the Safety and Efficacy of NDV-01 in Participants With NMIBC |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
CRVS |
Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma |
Trial Milestone |
Phase 3 |
| November 15, 2027 |
AURA |
A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma |
Trial Milestone |
Phase 3 |
| November 15, 2027 |
ANRO |
ALTO-207 in Adults With Treatment-resistant Depression (TRD) |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
COAG |
A Clinical Study to Assess Sutacimig in Participants With Congenital Factor VII Deficiency |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
MPLT |
ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD) |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
CRIS |
A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies |
Trial Milestone |
Phase 2 |
| November 15, 2027 |
BIOA |
A Randomized, Phase 2 Study of Oral BGE-102 in Participants With Center-Involved Diabetic Macular Edema |
Trial Milestone |
Phase 2 |
| November 16, 2027 |
NVO |
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy |
Trial Milestone |
Phase 2 |
| November 16, 2027 |
BIIB |
A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia |
Trial Milestone |
Phase 3 |
| November 21, 2027 |
MRNA |
Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in Participants With Solid Tumors |
Trial Milestone |
Phase 1 |
| November 22, 2027 |
REGN |
A Study to Learn How Safe and Tolerable Vonsetamig is in Adult Patients With Chronic Kidney Disease (CKD) Who Need Kidney Transplantation and Are Highly Sensitized to Human Leukocyte Antigen (HLA) |
Trial Milestone |
Phase 1/Phase 2 |
| November 24, 2027 |
AMGN |
A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL |
Trial Milestone |
Phase 1/Phase 2 |
| November 29, 2027 |
JAZZ |
A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures |
Trial Milestone |
Phase 1 |
| November 30, 2027 |
AZN |
Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma |
Trial Milestone |
Phase 2 |
| November 30, 2027 |
JAZZ |
JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors |
Trial Milestone |
Phase 1 |
| November 30, 2027 |
ADRX |
STOP-HAE: A Phase 3 Study of ADX-324 in HAE |
Trial Milestone |
Phase 3 |
| November 30, 2027 |
SRPT |
A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's Disease |
Trial Milestone |
Phase 1 |