| August 1, 2027 |
JAZZ |
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution |
Trial Milestone |
Phase 4 |
| August 1, 2027 |
VSTM |
Continued Access to Avutometinib in Combination With Defactinib in Patients With Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) |
Trial Milestone |
Phase 2 |
| August 3, 2027 |
IBRX |
NAI for Sepsis With Persistent Lymphopenia |
Trial Milestone |
Phase 2 |
| August 3, 2027 |
MRNA |
A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors |
Trial Milestone |
Phase 1 |
| August 5, 2027 |
GSK |
A Study to Evaluate the Subcutaneous Belantamab (BCMAb) Formulation Versus Intravenous Belantamab in Participants With Multiple Myeloma While Treated With Standard of Care |
Trial Milestone |
Phase 1 |
| August 5, 2027 |
JNJ |
A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN) |
Trial Milestone |
Phase 3 |
| August 5, 2027 |
JNJ |
A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms |
Trial Milestone |
Phase 1 |
| August 7, 2027 |
BIIB |
A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation |
Trial Milestone |
Phase 3 |
| August 9, 2027 |
ALNY |
A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy |
Trial Milestone |
Phase 2 |
| August 10, 2027 |
NVS |
A Study of Zigakibart in Adults With IgA Nephropathy |
Trial Milestone |
Phase 3 |
| August 10, 2027 |
REGN |
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) |
Trial Milestone |
Phase 1/Phase 2 |
| August 12, 2027 |
ACRV |
Study of ACR-2316 in Specific Advanced Solid Tumors |
Trial Milestone |
Phase 1/Phase 2 |
| August 15, 2027 |
LLY |
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
LLY |
A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
ABBV |
A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
GILD |
Substudy-01: A Study of Long-Acting HIV-1 Treatments Taken by Mouth in People With HIV-1 With Undetectable Virus Levels |
Trial Milestone |
Phase 2 |
| August 15, 2027 |
GILD |
A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1 |
Trial Milestone |
Phase 2 |
| August 15, 2027 |
IONS |
REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
NBIX |
Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia |
Trial Milestone |
Phase 2 |
| August 15, 2027 |
AAPG |
A Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL. |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
RARE |
A Study to Determine the Effect of Triheptanoin Compared With Even-Chain MCT on MCEs in Pediatric Patients With LC-FAOD |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
RARE |
Follow-up Study of AAV-Mediated Gene Transfer (UX111; Previously Known as ABO-102) for MPS Type IIIA |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
DFTX |
A Phase 2A Trial of DT402 for Autism Spectrum Disorder |
Trial Milestone |
Phase 2 |
| August 15, 2027 |
ACAD |
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response |
Trial Milestone |
Phase 2 |
| August 15, 2027 |
ASND |
A Study to Test the Effects and Safety of Palopegteriparatide in Adolescents With Long-term Hypoparathyroidism |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
SUPN |
RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures |
Trial Milestone |
Phase 2 |
| August 15, 2027 |
TVTX |
Pegtibatinase as a Treatment for Participants With Classical Homocystinuria (HCU) Receiving Standard of Care Treatment |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
PVLA |
A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU) |
Trial Milestone |
Phase 2 |
| August 15, 2027 |
LNTH |
Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy) |
Trial Milestone |
Phase 1/Phase 2 |
| August 15, 2027 |
TRVI |
Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine (NAL) Extended-Release (ER) Tablets |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
IRD |
OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
AVBP |
Phase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer. |
Trial Milestone |
Phase 1 |
| August 15, 2027 |
CLYM |
A Phase 1b/2a Study of Budoprutug in Subjects With Immune Thrombocytopenia (ITP) |
Trial Milestone |
Phase 1/Phase 2 |
| August 15, 2027 |
COAG |
A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia |
Trial Milestone |
Phase 1/Phase 2 |
| August 15, 2027 |
SGMT |
Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
LPCN |
Brexanolone Lifting Outcomes Of Moms |
Trial Milestone |
Phase 3 |
| August 15, 2027 |
CLLS |
Study Evaluating UCART20x22 in B-Cell Non-Hodgkin Lymphoma |
Trial Milestone |
Phase 1/Phase 2 |
| August 15, 2027 |
KPRX |
A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis Pigmentosa |
Trial Milestone |
Phase 2 |
| August 20, 2027 |
BNTX |
A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age |
Trial Milestone |
Phase 4 |
| August 20, 2027 |
ARWR |
A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE) |
Trial Milestone |
Phase 3 |
| August 23, 2027 |
NVS |
Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic Urticaria |
Trial Milestone |
Phase 2 |
| August 23, 2027 |
GSK |
A Study on the Long-term Efficacy, Safety and Persistence of Immune Response of a Vaccine Against Herpes Zoster in Older Adults |
Trial Milestone |
Phase 3 |
| August 24, 2027 |
ARGX |
A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS) |
Trial Milestone |
Phase 1 |
| August 29, 2027 |
INCY |
Extension Study to Provide Continued Treatment for Patients With Hematologic Malignancies Previously Enrolled in Studies With Tafasitamab |
Trial Milestone |
Phase 2 |
| August 30, 2027 |
AMGN |
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy |
Trial Milestone |
Phase 3 |
| August 30, 2027 |
ONCY |
FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer |
Trial Milestone |
Phase 2 |
| August 30, 2027 |
RADX |
A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors. |
Trial Milestone |
Phase 1 |
| August 30, 2027 |
APLM |
A Trial of "APL-9796'' in Adults With Pulmonary Hypertension |
Trial Milestone |
Phase 2 |
| August 31, 2027 |
AZN |
Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in Anifrolumab Users |
Trial Milestone |
Phase 4 |
| August 31, 2027 |
NVS |
Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency. |
Trial Milestone |
Phase 1 |
| August 31, 2027 |
REGN |
Short-Term Linvoseltamab Treatment on Top of Chronic Dupilumab Treatment for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy |
Trial Milestone |
Phase 1 |
| August 31, 2027 |
ALNY |
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM |
Trial Milestone |
Phase 1/Phase 2 |
| August 31, 2027 |
MRNA |
Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia |
Trial Milestone |
Phase 1/Phase 2 |
| August 31, 2027 |
MIRM |
Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide |
Trial Milestone |
Phase 2/Phase 3 |
| August 31, 2027 |
SRPT |
Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Participants With Duchenne Muscular Dystrophy Treated in a Post-Marketing Setting |
Trial Milestone |
Phase 4 |
| August 31, 2027 |
CANF |
An Open-label, Phase 2 Pilot Study on the Efficacy and Safety of Piclidenoson in Patients With Lowe Syndrome |
Trial Milestone |
Phase 2 |