Biotech catalysts, January 2027

53 tracked events across 37 companies

Clinical trial milestones, FDA decision dates, SEC filings and earnings scheduled for January 2027, compiled from ClinicalTrials.gov and SEC EDGAR.

DateTickerEventTypePhase
January 1, 2027 INCY A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation Trial Milestone Phase 1
January 2, 2027 est. ANGO Next quarterly earnings (projected) Earnings —
January 4, 2027 INCY A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Severe Renal Impairment or End Stage Renal Disease Trial Milestone Phase 1
January 4, 2027 MLTX Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response Trial Milestone Phase 3
January 6, 2027 INCY A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD Trial Milestone Phase 1/Phase 2
January 7, 2027 IDYA Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion Trial Milestone Phase 1
January 8, 2027 OCUL Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration Trial Milestone Phase 3
January 9, 2027 MRNA A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Formulations Trial Milestone Phase 4
January 11, 2027 est. JNJ Next quarterly earnings (projected) Earnings —
January 13, 2027 est. NRIX Next quarterly earnings (projected) Earnings —
January 14, 2027 NVO A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity Trial Milestone Phase 2
January 15, 2027 ABBV A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC) Trial Milestone Phase 2/Phase 3
January 15, 2027 ABBV Safety and Tolerability Study of Oral ABBV-744 Tablet Alone or in Combination With Oral Ruxolitinib Tablet or Oral Navitoclax Tablet in Adult Participants With Myelofibrosis Trial Milestone Phase 1
January 15, 2027 ABBV Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's Lymphoma Trial Milestone Phase 1
January 15, 2027 ABBV A Study to Assess Adverse Events, Tolerability, and Pharmacokinetics of Subcutaneous Injections of ABBV-295 in Healthy Adult Japanese Participants With Overweight or Obesity. Trial Milestone Phase 1
January 15, 2027 NVO A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure Trial Milestone Phase 1
January 15, 2027 SVA Phase Ⅲ Trial of Group ACYW135 Meningococcal Conjugate Vaccine in Children Aged 12-23 Months Trial Milestone Phase 3
January 15, 2027 RARE Setrusumab in Pediatric Japanese Subjects With Osteogenesis Imperfecta Trial Milestone Phase 3
January 15, 2027 MIRM A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis Trial Milestone Phase 2
January 15, 2027 PRAX Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures Trial Milestone Phase 3
January 15, 2027 XENE An Open-Label Study of Azetukalner in Major Depressive Disorder Trial Milestone Phase 3
January 15, 2027 IDYA IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma Trial Milestone Phase 2/Phase 3
January 15, 2027 TEVA A Trial to Assess TEV-56286 at Different Doses in Healthy Participants Trial Milestone Phase 1
January 15, 2027 PCVX Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Immunobridging to Adults 18-49 Trial Milestone Phase 3
January 15, 2027 RCUS A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies Trial Milestone Phase 2
January 15, 2027 NRIX A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies Trial Milestone Phase 1
January 15, 2027 EWTX A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX) Trial Milestone Phase 2
January 15, 2027 ELDN Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant Trial Milestone Phase 1/Phase 2
January 15, 2027 KURA KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors Trial Milestone Phase 1
January 15, 2027 PCRX Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery Trial Milestone Phase 1
January 15, 2027 LRMR An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia Trial Milestone Phase 2
January 15, 2027 SGMT Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne Trial Milestone Phase 1
January 15, 2027 LXRX A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy Trial Milestone Phase 3
January 15, 2027 XBIT Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment Trial Milestone Phase 2
January 15, 2027 CGEM CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) Trial Milestone Phase 1
January 16, 2027 CRBP A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors Trial Milestone Phase 1/Phase 2
January 18, 2027 PFE Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults. Trial Milestone Phase 3
January 20, 2027 TTRX A Double-Blind, Randomized, Vehicle-Controlled Phase 2 Study to Assess the Efficacy and Safety of GX-03 in Adult Subjects With Moderate to Severe Atopic Dermatitis (Eczema) Trial Milestone Phase 2/Phase 3
January 20, 2027 CELZ Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain Trial Milestone Phase 1/Phase 2
January 21, 2027 AMGN Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight Trial Milestone Phase 3
January 21, 2027 AMGN Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight Trial Milestone Phase 3
January 21, 2027 NVO A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or Obesity Trial Milestone Phase 1
January 21, 2027 TGTX Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab Trial Milestone Phase 3
January 22, 2027 ADRX Phase 1 Study of ADX-626 in Healthy Participants Trial Milestone Phase 1
January 26, 2027 NVO A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or Obese Trial Milestone Phase 1
January 28, 2027 MRNA A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults Trial Milestone Phase 3
January 29, 2027 IDYA Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions Trial Milestone Phase 1/Phase 2
January 30, 2027 SVA Immunogenicity and Safety of Rabies Vaccine (Serum-free Vero Cell) in a Simulated Post-exposure Prophylaxis Regimen Trial Milestone Phase 3
January 31, 2027 NVO A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity Trial Milestone Phase 1
January 31, 2027 EXEL Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors Trial Milestone Phase 1
January 31, 2027 QNRX Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome Trial Milestone Phase 2/Phase 3
January 31, 2027 BSX A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM Trial Milestone Phase 1
January 31, 2027 CELZ Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes Trial Milestone Phase 1/Phase 2

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INCY · ANGO · MLTX · IDYA · OCUL · MRNA · JNJ · NRIX · NVO · ABBV · SVA · RARE · MIRM · PRAX · XENE · TEVA · PCVX · RCUS · EWTX · ELDN · KURA · PCRX · LRMR · SGMT · LXRX · XBIT · CGEM · CRBP · PFE · TTRX · CELZ · AMGN · TGTX · ADRX · EXEL · QNRX · BSX